Endocrine Disrupting Contaminants and Reproductive Health: Alligators as Canaries in a Coal Mine

A conversation with Louis J. Guillette Jr., PhD, Professor of Obstetrics and Gynecology, Medical University of South Carolina; Centers of Economic Excellence (CoEE) Endowed Chair of Marine Genomics, Hollings Marine Laboratory; and Professor, Howard Hughes Medical Institute.

 

Wildlife have been used to predict detrimental human health effects of environmental contaminants for decades. There is growing concern about exposure to low levels of endocrine active contaminants early in embryonic development. Although each species is unique, molecular, cellular and physiological systems are conserved allowing insight on the process of human reproduction from wildlife studies.

Dr. Guillette will review the work done in his laboratory and others examining the effects of various environmental contaminants on the development and functioning of the ovary and reproductive system at the gene to organ level.

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